Tamsulosin 0.4mg 100's

Tamsulosin-Rex general information

What is Tamsulosin-Rex used for?

Tamsulosin-Rex capsules 0.4mg are used to treat functional symptoms of benign prostatic hyperplasia (BPH) in men with an enlarged prostate gland.  Tamsulosin-Rex 0.4mg relieves the symptoms of urinary retention caused by restricted urine flow as the prostate becomes enlarged and presses against the urethra (urine outlet tube from the bladder).  This helps urine to flow more easily, prevents urine backlog in the bladder, restores bladder control and relieves symptoms like need for frequent urination, inability to empty the bladder, strain and difficulty passing urine.  The improved urine flow and reduction in symptoms may reduce the need for surgery.

How does Tamsulosin-Rex work?

Tamsulosin-Rex capsules 0.4mg contain tamsulosin, an alpha₁-blocker (also known as alpha-adrenergic antagonist), that binds selectively to the alpha adrenergic receptor in smooth muscle of the prostate gland.  This receptor binding of tamsulosin in Tamsulosin-Rex capsules 0.4mg blocks the action of naturally occurring adrenergic chemicals like noradrenaline which causes smooth muscle cells to contract and tighten.  Benign prostatic hyperplasia (BPH) is due to overgrowth of the smooth muscle cells within the prostate gland and increased muscle tone of these cells.  Tamsulosin in Tamsulosin-Rex 0.4 relaxes these muscle cells which relieves the pressure exerted by the enlarged prostate gland on the urethra (urine outlet tube from the bladder); and also causes muscle cells in the neck of the bladder to relax.  The action of Tamsulosin in Tamsulosin-Rex 0.4 removes the blockage to urine flow caused by the enlarged prostate gland and allows urine to flow more freely through the urethra; it also relaxes the bladder neck, allowing urine to pass out of the bladder more easily.  Tamsulosin-Rex capsules 0.4mg are formulated for modified release, which means that the rate of absorption of the active ingredient tamsulosin into your blood is controlled and you need only take one capsule a day.  

What does Tamsulosin-Rex contain?

Tamsulosin-Rex capsules 0.4mg contain the active ingredient tamsulosin, an alpha₁-blocker used to treat urinary symptoms in benign prostatic hyperplasia (BPH).  They also contain: hypromellose, methacrylic-acid copolymer, triethyl citrate, propylene glycol, polysorbate 80, talc, ethyl cellulose, colloidal silicon dioxide, sugar, gelatine.

Treating urinary symptoms of benign prostatic hyperplasia (BPH) with Tamsulosin-Rex

Tamsulosin-Rex capsules 0.4mg contain tamsulosin, which is used to treat functional symptoms of benign prostatic hyperplasia (BPH) in men with an enlarged prostate gland.  BPH is due to overgrowth of the smooth muscle cells within the prostate gland and increased muscle tone of these cells, which causes the prostate gland to compress the urethra (urine outlet tube from the bladder) running through the gland and obstructs urine flow.  Tamsulosin in Tamsulosin-Rex capsules 0.4mg is an alpha₁-blocker (also known as alpha-adrenergic antagonist) that binds selectively to the alpha adrenergic receptor in smooth muscle of the prostate gland and blocks the action of naturally occurring adrenergic chemicals like noradrenaline, which causes smooth muscle cells to contract and tighten.  Tamsulosin-Rex 0.4 relaxes the smooth muscle cells in the prostate gland and removes the pressure against the urethra, allowing urine to flow more freely through the urethra; and also relaxes the bladder neck, allowing urine to pass out of the bladder more easily.  This action relieves symptoms like need for frequent urination, inability to empty the bladder, strain and difficulty passing urine.  The improved urine flow and reduction in symptoms may reduce the need for surgery.

What are the side effects of Tamsulosin-Rex?

The most commonly reported side effects when taking Tamsulosin-Rex capsules 0.4mg include: dizziness, headache, abnormal ejaculation, asthenia (weakness), postural hypotension (dizziness on standing) and palpitations.  A less common side effect is a persistent painful erection which should be reported to your doctor.

When should Tamsulosin-Rex not be used?

You should not use Tamsulosin-Rex capsules 0.4mg if you:

• are allergic to tamsulosin or any ingredients in Tamsulosin-Rex
• have kidney or liver disease
• have a history of orthostatic hypotension (dizziness, weakness when standing up from sitting)
• are taking medications that interact with Tamsulosin-Rex, including: other alpha-blockers that relaxes smooth muscle, the antiinflammatory diclofenac, the anticoagulant warfarin, cimetidine for stomach ulcers

How should Tamsulosin-Rex be taken?

You should take your Tamsulosin-Rex capsules 0.4mg swallowed whole with a glass of water, once daily, 30 minutes after your first meal of the day.  You should continue to take your Tamsulosin-Rex 0.4 for 2-4 weeks; if your symptoms have not improved, your doctor may increase you dose.

How long should you take Tamsulosin-Rex?

You should continue to take your Tamsulosin-Rex capsules 0.4mg continually for 2-4 weeks, if you miss a few days you may need to begin your course of treatment again.

Missed dose of Tamsulosin-Rex

If you miss a dose of Tamsulosin-Rex capsules 0.4mg take it as soon as you remember, unless it is time to take the next dose, then skip the missed dose.  Do not take a double dose.

How should Tamsulosin-Rex be stored?

You should Store your Tamsulosin-Rex capsules 0.4mg in their blister strips until use and in a cool dry place at room temperature below 25°C; keep out of direct sunlight.