Dynapres 0.4mg (Tamsulosin) Prolonged Release

Dynapres general information

What is Dynapres used for?

Dynapres capsules 0.4mg are used to treat functional symptoms of benign prostatic hyperplasia (BPH) in men with an enlarged prostate gland. Dynapres 0.4 relieves the symptoms of urinary retention caused by restricted urine flow as the prostate becomes enlarged and presses against the urethra (urine outlet tube from the bladder), which helps urine to flow more easily, prevents urine backlog in the bladder and restores bladder control. This relieves symptoms like need for frequent urination, inability to empty the bladder, strain and difficulty passing urine. The improved urine flow and reduction in symptoms may reduce the need for surgery.

How does Dynapres work?

Dynapres capsules 0.4mg contain tamsulosin, an alpha1-blocker (also known as alpha-adrenergic antagonist), that binds selectively to the alpha adrenergic receptor in smooth muscle of the prostate gland and blocks the action of naturally occurring adrenergic chemicals like noradrenaline which causes smooth muscle cells to contract and tighten. Benign prostatic hyperplasia (BPH) is due to overgrowth of the smooth muscle cells within the prostate gland and increased muscle tone of these cells. Tamsulosin in Dynapres 0.4 relaxes these muscle cells which relieves the pressure exerted by the enlarged prostate gland on the urethra (urine outlet tube from the bladder); and also causes muscle cells in the neck of the bladder to relax. The action of Tamsulosin in Dynapres 0.4 removes the blockage to urine flow caused by the prostate gland and allows urine to flow more freely through the urethra; it also relaxes the bladder neck, allowing urine to pass out of the bladder more easily. Dynapres capsules 0.4mg are formulated for modified release, which means that the rate of absorption of the active ingredient tamsulosin into your blood is controlled and you need only take one capsule a day.

What does Dynapres contain?

Dynapres capsules 0.4mg contain the active ingredient tamsulosin, an alpha1-blocker used to treat urinary symptoms in benign prostatic hyperplasia (BPH).

Treating urinary symptoms of benign prostatic hyperplasia (BPH) with Dynapres

Dynapres capsules 0.4mg contain tamsulosin, which is used to treat functional symptoms of benign prostatic hyperplasia (BPH) in men with an enlarged prostate gland. BPH is due to overgrowth of the smooth muscle cells within the prostate gland and increased muscle tone of these cells, which causes the prostate glad to compress the urethra (urine outlet tube from the bladder) running through the gland and obstructs urine flow. Tamsulosin in Dynapres capsules 0.4mg is an alpha1-blocker (also known as alpha-adrenergic antagonist), that binds selectively to the alpha adrenergic receptor in smooth muscle of the prostate gland and blocks the action of naturally occurring adrenergic chemicals like noradrenaline which causes smooth muscle cells to contract and tighten. Dynapres 0.4 relaxes the smooth muscle cells in the prostate gland and removes the pressure against the urethra, allowing urine to flow more freely through the urethra; and also relaxes the bladder neck, allowing urine to pass out of the bladder more easily. This action relieves symptoms like need for frequent urination, inability to empty the bladder, strain and difficulty passing urine. The improved urine flow and reduction in symptoms may reduce the need for surgery.

What are the side effects of Dynapres?

The most commonly reported side effects when taking Dynapres capsules 0.4mg include: dizziness, headache, abnormal ejaculation, asthenia (weakness), postural hypotension (dizziness on standing) and palpitations. A less common side effect is a persistent painful erection which should be reported to your doctor.

When should Dynapres not be used?

You should not use Dynapres capsules 0.4mg if you:

• are allergic to tamsulosin or any ingredients in Dynapres 0.4
• have liver or kidney disease
• have a history of orthostatic hypotension (dizziness, weakness)
• are taking medications that interact with Dynapres, including: other alpha-blockers that relaxes smooth muscle, the antiinflammatory diclofenac, the anticoagulant warfarin, cimetidine for stomach ulcers

How should Dynapres be taken?

You should take your Dynapres capsules 0.4mg swallowed whole with a glass of water, once daily 30 minutes after your first meal of the day. You should continue to take your Dynapres 0.4 for 2-4 weeks; if your symptoms have not improved, your doctor may increase you dose.

How long should you take Dynapres?

You should continue to take your Dynapres capsules 0.4mg continually for 2-4 weeks, if you miss a few days you may need to begin your course of treatment again.

Missed dose of Dynapres

If you miss a dose of Dynapres capsules 0.4mg, take it as soon as you remember, unless it is time to take the next dose, then skip the missed dose. Do not take a double dose.

How should Dynapres be stored?

You should Store your Dynapres capsules 0.4mg in a cool dry place at room temperature below 30°C, and keep out of direct sunlight.