Tofabrint (Tofacitinib 5mg) Tablets

Tofabbrint general information


What is Tofabrint 5mg tablets used for?

Tofabrint 5 mg Tablet is a Janus kinase inhibitor used to treat rheumatoid arthritis, psoriatic arthritis, and ulcerative colitis. These conditions involve autoimmune or inflammatory processes affecting joints or the large intestine, leading to symptoms like joint pain, damage, and intestinal inflammation.

How does Tofabrint 5mg tablets work?

Tofabrint 5 mg (tofacitinib) works by blocking enzymes called Janus kinases (JAKs), which are involved in the body's immune response and inflammation pathways. By inhibiting JAKs, Tofabrint reduces inflammation and symptoms in conditions like rheumatoid arthritis, psoriatic arthritis, and ulcerative colitis, where excessive immune activity causes joint damage or bowel inflammation. This helps to manage these chronic inflammatory conditions effectively.

What does Tofabrint 5mg tablets contain?

The active ingredient in Tofabrint 5 mg tablets is tofacitinib citrate. Tofacitinib citrate is a Janus kinase (JAK) inhibitor, which means it targets and inhibits specific enzymes involved in inflammatory pathways in the body.

What are the side effects of Tofabrint 5mg tablets?

The most commonly reported side effects when taking Tofabrint 5mg tablets include, headache, diarrhoea, vomiting, nausea, upper respiratory tract infection, cold, and high blood pressure.

When should Tofabrint 5mg tablets not be used?

You should not use Tofabrint 5 mg if you are allergic to any of its ingredients, have a severe infection, bloodstream infection, active tuberculosis, or severe liver problems like cirrhosis. Avoid this medication if you are pregnant or breastfeeding. Inform your doctor if you have an infection or symptoms thereof, any condition predisposing to infections, are taking immunosuppressive medications, have a history of tuberculosis or recent exposure to it, chronic lung disease, liver disease including hepatitis B/C, cancer, increased risk of skin cancer, inflammation or ulcers of the large intestine, kidney problems, planning vaccinations, heart issues, high cholesterol, hypertension, previous heart attack, diabetes, or blood clotting disorders. Refrain from using Tofabrint 5 mg Tablet if your white blood cell or red blood cell counts are low. This medication is not suitable for children under 18 years old due to lack of established safety and efficacy. Keep your doctor informed about your health status and current medications to prevent potential adverse effects.

What medications interact with Tofabrint 5mg tablets?

Tofabrint 5 mg Tablets may interact with antibiotic (rifampicin), anti-fungal (fluconazole, ketoconazole), immunosuppressant (azathioprine, mercaptopurine, cyclosporine, tacrolimus), corticosteroids (prednisone).

How should Tofabrint 5mg tablets be used?

You should take your Tofabrint 5mg tablets as directed by your physician with or without food. Do not chew or break it.

How long should you use/give Tofabrint 5mg?

You should continue to take tofabrint 5mg tablets for as long as recommended by your physician.

Missed dose of Tofabrint 5mg tablets.

If you miss a dose of Tofabrint 5mg tablets take it as soon as you remember, unless it is time to take the next dose, then skip the missed dose.  Do not take a double dose.

How should Tofabrint 5mg tablets be stored?

You should Store your Tofabrint 5mg tablets in a cool and dry place away from sunlight.