Celecoxib 100mg Pfizer

Celecoxib Pfizer general information

What is Celecoxib Pfizer used for?

Celebrex Pfizer capsules 100mg are used to treat chronic inflammatory diseases such as osteoarthritis, rheumatoid arthritis and ankylosing spondylitis, to reduce pain, inflammation, tenderness, stiffness and swelling in the affected joints.  They are also used for the management of acute pain and treatment of dysmenorrhea (menstrual pain), when sufficient pain relief from other medications has not been achieved.  Celebrex capsules 100mg does not cure arthritic disease but can relieve symptoms of pain and inflammation and improve the functional use of affected joints.

How does Celecoxib Pfizer work?

Celecoxib Pfizer capsules 100mg contain celecoxib, which is a nonsteroidal anti-inflammatory drug (NSAID) that works by blocking the production of specific chemicals called prostaglandins (PG) that mediate inflammation.  Celecoxib in Celecoxib Pfizer capsules 100mg is a specific inhibitor of the enzyme cyclooxygenase 2 (COX-2) that is induced during the inflammation process and is responsible for the synthesis of inflammatory prostaglandins like PGE2, which causes pain, swelling and other symptoms of inflammation.  Celecoxib Pfizer also has anti-pyretic action (reduces fever) but has no effect on the cyclooxygenase 1 enzyme (COX-1) that is needed for normal cellular processes.  By inhibiting the action of COX-2 Celecoxib Pfizer capsules 100mg relieve the symptoms of inflammation, including pain, swelling, and joint stiffness.

What does Celecoxib Pfizer contain?

Celecoxib Pfizer capsules 100mg contain the active ingredient Celecoxib Pfizer, a nonsteroidal anti-inflammatory drug (NSAID) and specific inhibitor of the enzyme cyclooxygenase 2 (COX-2) that reduces pain and inflammation.  They also contain: lactose, sodium lauryl sulphate, povidone, croscarmellose sodium, magnesium stearate, gelatine, titanium dioxide, indigo carmine CI 73015.

Treating arthritis with Celecoxib Pfizer

Celecoxib Pfizer capsules 100mg contain celecoxib, which is a nonsteroidal anti-inflammatory drug (NSAID) and a specific inhibitor of the enzyme cyclooxygenase 2 (COX-2) that is induced during the inflammation process and is responsible for the synthesis of inflammatory chemicals called prostaglandins (PG), particularly PGE2.  Osteoarthritis and rheumatoid arthritis are chronic inflammatory diseases in which the joints become inflamed, swollen and painful.  Celecoxib in Celecoxib Pfizer capsules 100mg help relieve the pain, swelling and other symptoms of inflammation by inhibiting the action of COX-2 therefore blocking PGE2 production.  This action reduces pain and inflammation, and improves the functional use of the arthritic joint.

Celecoxib Pfizer for pain and inflammation

Celecoxib Pfizer capsules 100mg contain celecoxib, which is a nonsteroidal anti-inflammatory drug (NSAID) and a specific inhibitor of the enzyme cyclooxygenase 2 (COX-2) that is induced during the inflammation process and is responsible for the synthesis of inflammatory chemicals called prostaglandins (PG), particularly PGE2.  Celecoxib Pfizer capsules 100mg are used to treat chronic inflammatory diseases such as osteoarthritis, rheumatoid arthritis and ankylosing spondylitis, to reduce pain, inflammation, tenderness, stiffness and swelling in the affected joints.  They are also used for the management of acute pain and treatment of dysmenorrhea (menstrual pain) in people who have not been able to achieve sufficient pain relief from other medications.  

What are the side effects of Celecoxib Pfizer?

The most commonly reported side effects when taking Celecoxib Pfizer capsules 100mg are gastrointestinal and include: upset stomach or stomach pain, diarrhoea, indigestion, bloating wind.  Other side effects include: dizziness, sinusitis and upper respiratory tract infection, blurred vision, skin rash and itching, swollen hands, ankles and feet.  More serious but rare side effects include gastric ulceration and bleeding and cardiovascular events including heart attack.

When should Celecoxib Pfizer not be used?

You should not use Celecoxib Pfizer capsules 100mg if you:

• are allergic to celecoxib, aspirin or any other nonsteroidal anti-inflammatory drug (NSAID), or any ingredients in Celecoxib Pfizer
• are pregnant or breastfeeding
• have an allergy to sulphonamides
• have asthma
• have an ulcer, gastric bleeding, irritable bowel disease or heart failure
• have kidney or liver disease
• are taking medicines that interact with Celecoxib Pfizer including: other NSAIDs, aspirin, anticoagulants like warfarin, oral corticosteroids, the antifungal drug fluconazole, diuretics like furosemide, lithium for depression, ACE inhibitors for high blood pressure, antacids for indigestion.

What medications interact with Celecoxib Pfizer?

Several medications interact with Celecoxib Pfizer capsules 100mg and should either not be taken while you are taking Celecoxib or only after discussion and instruction from your doctor:

• Drugs that cause a serious reaction with Celecoxib: anticoagulants like warfarin, also glucocorticoids  increase risk of bleeding; diuretics like furosemide and ACE inhibitors for high blood pressure increases risk of kidney problems; aspirin can increase risk of gastric ulcers
• Drugs that affect Celecoxib: , the antifungal drug fluconazole, antacids for indigestion
• Drugs that are affected by Celecoxib: lithium for depression, digoxin for heart failure

How should Celecoxib Pfizer be taken?

You should take your Celecoxib Pfizer capsules 100mg once or twice daily, with or without food.  However, if your Celecoxib Pfizer capsules upset your stomach, then you should take them with food.  The dose you take and for how long depends on what you are being treated for and as recommended by your doctor, which may be for a few days, several weeks or longer. 

How long should you take Celecoxib Pfizer?

You should continue to take your Celecoxib Pfizer capsules 100mg for as long as recommended by your doctor, which may be for a few days, several weeks or longer, depending on what you are being treated for.

Missed dose of Celecoxib Pfizer

If you miss a dose of Celecoxib Pfizer capsules 100mg take it as soon as you remember, unless it is time to take the next dose, then skip the missed dose.  Do not take a double dose.

How should Celecoxib Pfizer be stored?

You should store your Celecoxib Pfizer capsules 100mg below 25°C in a cool dry place.