LQuin (Levofloxacin) 750mg Tablets

General information

What is LQuin used for?

LQuin tablets 750mg are an antibiotic medication used to treat mild, moderate and severe bacterial infections, caused by a wide range of susceptible bacteria in various parts of the body.  LQuin tablets 750mg are used to treat pneumonia, both community acquired, which is one of the most common serious infectious diseases, usually caused by Streptococcus pneumoniae; also nosocomial pneumonia, which is hospital-acquired pneumonia contracted within 48-72 hours of admission.  LQuin tablets 750mg are also used to treat acute bacterial sinusitis and acute exacerbations of chronic bronchitis.  Other non-respiratory infections that LQuin tablets 750mg are used to treat include, complicated skin and soft tissue infections, which involve deeper infections such as infected ulcers, burns, and major abscesses usually due to Staphylococcus aureus, but also due to Enterococcus faecalis, Streptococcus pyogenes or Proteus mirabilis; also uncomplicated skin and skin structure infections (mild to moderate), including abscesses, cellulitis, furuncles, impetigo, pyoderma and wound infections, due to methicillin-susceptible Staphylococcus aureus or Streptococcus pyogenes.  LQuin tablets 750mg are also used to treat infections of the urogenital system, including pyelonephritis (infection and inflammation of the kidney), complicated urinary tract infections, chronic bacterial prostatitis (infection and inflammation of the prostate), and uncomplicated cystitis.  LQuin tablets 750mg may be used after anthrax inhalation, as post exposure prophylaxis to reduce risk of pulmonary disease.

How does LQuin work?

LQuin tablets 750mg contain levofloxacin, a synthetic broad spectrum antibiotic of the fluoroquinolone class that is used to treat various infections with antibacterial activity against a wide range of bacteria, including Staphylococcus, Streptococcus Enterococcus, Proteus and Haemophilus.  Levofloxacin works by inhibiting several bacterial enzymes (bacterial topoisomerase IV and DNA gyrase) needed for the bacteria to replicate and repair its DNA.  This action of levofloxacin in LQuin tablets 750mg kills the bacteria by blocking its growth and prevents spread of infection.  LQuin tablets 750mg do not work against viruses which use a different mechanism to grow and replicate. 

What does LQuin contain?

LQuin tablets 750mg contain the active ingredient levofloxacin, a synthetic broad spectrum antibiotic of the fluoroquinolone class that is used to treat a wide range of infections caused by a many susceptible bacteria in various parts of the body.

Treating bacterial infection with LQuin

LQuin tablets 750mg contain levofloxacin, a synthetic broad spectrum antibiotic that is used to treat a wide range of infections caused by a many susceptible bacteria in various parts of the body, including Staphylococcus, Streptococcus Enterococcus, Proteus and Haemophilus.  LQuin tablets 750mg are used to treat pneumonia, both community acquired and nosocomial pneumonia; acute bacterial sinusitis; acute exacerbations of chronic bronchitis; complicated skin and soft tissue infections such as infected ulcers, burns, and major abscesses; uncomplicated skin and skin structure infections (mild to moderate), including abscesses, cellulitis, furuncles, impetigo, pyoderma and wound infections; pyelonephritis (infection and inflammation of the kidney); complicated urinary tract infections and uncomplicated cystitis; chronic bacterial prostatitis (infection and inflammation of the prostate).  LQuin tablets 750mg may be used after anthrax inhalation, as post exposure prophylaxis to reduce risk of pulmonary disease.  Levofloxacin in LQuin tablets 750mg works by inhibiting several bacterial enzymes needed for the bacteria to replicate and repair its DNA, which kills the bacteria by blocking its growth and preventing spread of infection. 

What are the side effects of LQuin?

The most commonly reported side effects when taking LQuin tablets 750mg include insomnia, headache, dizziness, diarrhoea, vomiting, nausea, abdominal pain, constipation, headache, rash, altered taste.  Very rarely taking LQuin tablets 750mg is associated with an increased risk of tendonitis and tendon rupture with increased risk if you are over the age of 60 years, taking systemic steroids or have received a kidney, heart or lung transplant. 

When should LQuin not be used?

You should not use LQuin tablets 750mg if you:

• are allergic to levofloxacin or any ingredients in LQuin
• are pregnant or are breastfeeding
• have liver or kidney disease
• have epilepsy or myasthenia gravis
• have a history of tendon disorders related to levofloxacin administration
• have diabetes as LQuin can affect blood glucose levels and these should be closely monitored while taking LQuin
• are giving LQuin to children or growing adolescents
• are taking medicines that interact with LQuin including sucralfate for reflux and ulcers, antacids containing magnesium and  aluminium, multivitamins preparations with zinc, the antiviral didanosine, some NSAIDs like theophylline, probenecid for gout, cimetidine for heartburn and ulcers, , the immunosuppressant cyclosporine, anticoagulants like warfarin

What medications interact with LQuin?

Several medications interact with LQuin tablets 750mg and should either not be taken while you are taking LQuin or only after discussion and instruction from your doctor:

• Drugs that cause a serious reaction with LQuin: some NSAIDs like theophylline,
• Drugs that affect LQuin: sucralfate for reflux and ulcers, antacids containing magnesium and  aluminium, multivitamins preparations with zinc, the antiviral didanosine, probenecid for gout, cimetidine for heartburn and ulcers
• Drugs that are affected by LQuin: , the immunosuppressant cyclosporine, anticoagulants like warfarin

How should LQuin be taken?

You should take your LQuin tablets 750mg swallowed whole with a glass of water with or without food, once or twice daily.  The dose you take and how often depends on what you are being treated for and your doctor’s recommendations.  You should continue to take your LQuin tablets 750mg for as long as recommended by your doctor, which is usually for 7 to 14 days, but the dose or length of time you need to take your tablets for may be increased depending on the severity of your infection and your response to treatment. 

How long should you take LQuin?

You should continue to take your LQuin tablets 750mg for as long as recommended by your doctor, which is usually for 7 to 14 days, but the dose or length of time you need to take your tablets for may be increased depending on the severity of your infection and your response to treatment. 

Missed dose of LQuin

If you miss a dose of LQuin tablets 750mg take it as soon as you remember, unless it is time to take the next dose, then skip the missed dose.  Do not take a double dose.

How should LQuin be stored?

You should store your LQuin tablets 750mg below 25°C in a cool dry place.