Bioclan (Clindamycin 25mg/ml)

Bioclan general information

What is Bioclan used for?

Bioclan oral solution 25mg/ml is an antibiotic medication used for the treatment of serious bacterial infections in cats and dogs caused by susceptible bacteria.  These include superficial pyoderma (superficial skin infection), wounds and abscesses, infected mouth cavity and dental infections; also to prevent infection due to dental surgery.  In dogs Bioclan oral solution 25mg/ml/ml is also used to treat osteomyelitis (infection of the bone or bone marrow), which may be caused by an infection from another part of the body reaching the bone through the blood, or the bone may become infected from an accident involving the bone.  Bioclan oral solution 25mg/ml is specially formulated for treatment of bacterial infections in dogs and cats.

How does Bioclan work?

Bioclan oral solution 25mg/ml contains clindamycin, a lincosamide antibiotic with bacteriostatic action that is used to treat a wide range of serious bacterial infections in cats and dogs.  Clindamycin in Bioclan oral solution 25mg/ml is effective against a range of sensitive bacteria including Staphylococcus aureus and intermedius, Bacteroides fragilis, Prevotella melaninogenicus, Fusobacterium necrophorum and Clostridium perfringens.  Clindamycin in Bioclan oral solution 25mg/ml works by binding to the bacterial ribosome, a structure involved in protein synthesis and this inhibits the early stages of bacterial protein synthesis, so that the bacteria cannot make important proteins required for survival of the bacteria, which inhibits bacterial growth and prevents the spread of infection.  Clindamycin in Bioclan oral solution 25mg/ml is lipid soluble and therefore, penetrates many body fluids and tissues, such as soft tissue, bone and joints; it also penetrates biofilms found in dental and bone infections.  It is rapidly absorbed and concentrates in the white blood cells at the site of infection.  

What does Bioclan contain?

Bioclan oral solution 25mg/ml contain the active ingredient clindamycin hydrochloride, an antibiotic that is used to treat a wide range of serious bacterial infections in cats and dogs.  It also contains isopropyl alcohol.

Treating bacterial infection with Bioclan

Bioclan oral solution 25mg/ml contains clindamycin, an antibiotic that is used to treat a wide range of serious bacterial infections in cats and dogs.  These include superficial pyoderma (superficial skin infection), wounds and abscesses, infected mouth cavity and dental infections; also to prevent infection due to dental surgery.  In dogs Bioclan oral solution 25mg/ml is also used to treat osteomyelitis (infection of the bone).  Clindamycin in Bioclan oral solution 25mg/ml works by binding to the bacterial ribosome, a structure involved in protein synthesis and this inhibits the early stages of bacterial protein synthesis, so that the bacteria cannot make important proteins required for survival of the bacteria, which inhibits bacterial growth and prevents the spread of infection. 

What are the side effects of Bioclan?

The most commonly reported side effects when taking Bioclan oral solution 25mg/ml include vomiting and diarrhoea.  Clindamycin may cause overgrowth of non-sensitive organisms like yeast and the toxin-producing bacterium clostridium in the intestines, which can cause intestinal problems.

When should Bioclan not be given?

You should not give Bioclan oral solution 25mg/ml to your pet if your pet:

• is allergic to clindamycin or any ingredients in Bioclan
• is pregnant or lactating
• has kidney or liver disease
• is taking medicines that interact with Bioclan including the antibiotic erythromycin; neuromuscular blockers

How should Bioclan be given?

You should give your pet Bioclan oral solution 25mg/ml once or twice daily depending on what they are being treated for using the calibrated dosing syringe provided, and the dose given should be according to body weight.  You should continue to give Bioclan oral solution 25mg/ml for as long as recommended by your veterinary professional which ranges from 14-28 days, depending on what your pet is being treated for.

Dosage for dogs:

For general infection: 5.5 -33 mg/kg (2.5-15mg/lb) every 12 hours for a maximum of 28 days, discontinue if no effect within 3-4 days

For osteomyelitis: 11 -33mg/kg (5-15mg/lb) every 12 hours for a maximum of 28 days. 

Dosage for cats:

For general infection: 11 -33mg/kg (5-15mg/lb) every 24 hours for a maximum of 14 days, discontinue if no effect within 3-4 days.

How long should you take Bioclan?

You should continue to give Bioclan oral solution 25mg/ml for as long as recommended by your veterinary professional which ranges from 14-28 days, depending on what your pet is being treated for.

Missed dose of Bioclan

If you miss a dose of Bioclan oral solution 25mg/ml give it as soon as you remember, unless it is time to give the next dose, then skip the missed dose.  Do not give a double dose.

How should Bioclan be stored?

You should store your Bioclan oral solution 25mg/ml below 25°C in a cool dry place.