Vedafil (Sildenafil Citrate 50mg) Tablets

Vedafil general information

What is Vedafil used for?

Vedafil tablets 50mg are used to treat erectile dysfunction (impotence) in men, which is the inability to achieve or maintain a hard erect penis suitable for sexual activity, due to insufficient blood flow into the penis.  Vedafil tablets 50mg relax the blood vessels in the penis increasing blood flow and causing an erection, which is the natural response to sexual stimulation.  However, Vedafil tablets 50mg will only work if you are sexually aroused.

How does Vedafil work?

Vedafil tablets 50mg contain sildenafil which acts on the erectile tissue of the penis to increase blood flow which causes an erection.  During sexual stimulation nitric oxide is released in the erectile tissue of the penis which activates the enzyme guanylate cyclase.  This enzyme increases levels of a chemical called cyclic guanosine monophosphate (cGMP), which relaxes the blood vessels in the penis and allows blood to fill the spongy erectile tissues to cause an erection.  Another enzyme called phosphodiesterase type 5 (PDE5) breaks down cGMP preventing blood flow into the penis, which causes loss of an erection.  Vedafil tablets 50mg inhibit the action of PDE5 which resolves erectile dysfunction by allowing the natural process of sexual stimulation to activate the cGMP mechanism for achieving and maintaining an erection. 

How long does Vedafil last?

Vedafil tablets 50mg should be taken within an hour of planned sex and in most cases, it helps you to get an erection in about 30 minutes that will last for around 4 hours, provided you are sexually aroused.  Vedafil tablets 50mg do not work if you are not aroused.

What does Vedafil contain?

Vedafil tablets 50mg contain the active ingredient sildenafil which is used to treat erectile dysfunction (impotence) in men.  Vedafil tablets 50mg also contain microcrystalline cellulose, calcium hydrogen phosphate anhydrous, croscarmellose sodium, magnesium stearate, hypromellose, titanium dioxide, indigo carmine (FD&C), triacetin.

Treating erectile dysfunction (impotence) with Vedafil

Vedafil tablets 50mg contain sildenafil, a phosphodiesterase type 5 (PDE5) inhibitor, used to treat erectile dysfunction in men (impotence).  When taken before planned sexual activity, Vedafil tablets 50mg inhibit the breakdown (by the enzyme PDE5) of a chemical called cGMP, produced in the erectile tissue of the penis during sexual arousal, and this action allows blood flow into the penis causing an erection. 

What are the side effects of Vedafil?

The most commonly reported side effects when taking Vedafil tablets 50mg include headache, dizziness, flushing, indigestion, nasal congestion, diarrhoea, rash.  More serious side effects include unusual heartbeat, urinary tract infection (stinging or burning urine, more frequent need to pass urine), blood in the urine, changes in vision such as blurring, a blue colour to your vision or a greater awareness of light, persistent headache or fainting, bleeding from the nose.

When should Vedafil not be used?

You should not use Vedafil tablets 50mg if you:

• are allergic to sildenafil or any ingredients in Vedafil
• are a woman, Vedafil is only intended for use by men
• have a condition where sexual intercourse inadvisable due to cardiovascular or heart problems or you have had a heart attack or stroke in the last 6 months
• have liver disease
• have abnormally high or low blood pressure
• have an eye disease like non-arteritic anterior ischaemic optic neuropathy (NAION), which causes loss of vision or if you have retinitis pigmentosa
• are taking medication that may interact with Vedafil or may increase your risk for side-effects, including cimetidine for treating ulcers, antibiotics like erythromycin and rifampicin, verapamil or diltiazem (for high blood pressure), ritonavir or saquinavir (for HIV), itraconazole or ketaconazole (for fungal infections) alpha-blockers; like amlodipine for high blood pressure.

How should Vedafil be taken?

You should take one Vedafil tablet 50mg with a glass of water approximately one hour before sexual activity and without food.  If you have a large meal before taking your Vedafil 50mg tablet it may take longer to work.  You should take no more than one tablet a day and only if you plan to have sex.

Missed dose of Vedafil

You should only take a Vedafil 50mg tablet when you plan to have sex; it is not intended as a regular medication. 

How should Vedafil be stored?

You should store your Vedafil tablets 50mg below 25°C in a cool dry place.