Panzop Relief 40mg (Pantoprazole)

Panzop Relief general information

What is Panzop Relief used for?

Panzop Relief tablets 40mg are used to treat conditions caused by gastric reflux, which is when the acidic contents of the stomach flow back into the oesophagus because the sphincter (muscle at the junction of the oesophagus and stomach) that normally acts as a one-way valve and prevents backflow of stomach contents, does not function properly or is damaged.  Gastroesophageal reflux disease (GORD), as this condition is known, causes symptoms like heartburn and dyspepsia (indigestion and abdominal pain), and can damage the oesophagus causing inflammation (oesophagitis).  Panzop Relief 40 is also used to treat and prevent peptic ulcers in the stomach (gastric ulcers or damage to the stomach lining) and duodenum (duodenal ulcers or damage to the lining of the upper intestine); and gastric ulcers caused by use of nonsteroidal anti-inflammatory drugs (NSAID); also as combination therapy to treat gastric ulcers that are caused by infection of the stomach with the bacterium Helicobacter pylori, in conjunction with using antibiotics.  Panzop Relief tablets 40mg are also used to treat symptoms of acid-related dyspepsia that can be caused by eating high fat or acidic foods, or Zollinger-Ellison syndrome in which increased levels of the hormone gastrin causes an excessive production of gastric acid.

How does Panzop Relief work?

Panzop Relief tablets 40mg contain pantoprazole, a proton pump inhibitor that is used to treat conditions caused by excess gastric acid, by reducing the amount of gastric acid released into the stomach.  Stomach acid is needed for digestion of proteins in the diet and is made by the parietal cells of the stomach wall.  Gastric acid production is dependent on the action of the enzyme H⁺/K⁺-ATPase, which is the proton pump responsible for pumping positive hydrogen ions out of the cells into the stomach; and this increases the acidity of the stomach contents.  Pantoprazole in Panzop Relief 40 is converted to its active form in the parietal cells where it inhibits the functioning of the H⁺/K⁺-ATPase, which prevents acid secretion by blocking the source of acid production.  This action of pantoprazole in Panzop Relief tablets 40mg reduces the acidity of the stomach contents, which reduces the acid damage that can be caused by gastroesophageal reflux disease (GORD) and oesophagitis and relieves symptoms caused by excess gastric acid, like heartburn and dyspepsia.  By inhibiting gastric acid secretion Panzop Relief tablets 40mg also help prevent the formation of gastric (stomach) and duodenal (upper intestine) peptic ulcers and also acid digestion in the stomach, allowing ulcers and damage caused by gastric reflux to heal.  Panzop Relief tablets 40mg are formulated for delayed release to prevent the active ingredient them being released too early due to stomach acid.

What does Panzop Relief contain?

Panzop Relief tablets contain the active ingredient pantoprazole sodium sesquihydrate (40mg), which is a proton pump inhibitor that is used to treat conditions caused by excess gastric acid secretion.  They also contain: sodium carbonate, mannitol, crospovidone, povidone, calcium stearate, eudragit, triethyl citrate, black printing ink and opadry yellow OY-52945 (contains hypromellose, titanium dioxide, macrogol and iron oxide yellow).

Treating gastric reflux with Panzop Relief

Panzop Relief tablets 40mg contain pantoprazole, which is used to treat conditions caused by gastroesophageal reflux disease (GORD).  Gastric reflux is when the acidic contents of the stomach flow back into the oesophagus (gullet), because the sphincter muscle at the junction of the oesophagus and stomach that normally prevents backflow of stomach contents, does not function properly or is damaged.  Symptoms caused by gastric reflux include heartburn and dyspepsia (indigestion and abdominal pain), and damage to the oesophagus causing inflammation (oesophagitis).  Pantoprazole in Panzop Relief 40 reduces acid secretion by parietal cells of the stomach wall, by blocking the action of the enzyme H⁺/K⁺-ATPase, which is responsible for acid production.  This action of pantoprazolein Panzop Relief tablets 40mg reduces the acidity of the stomach contents, which reduces the acid damage that can be caused by gastroesophageal reflux disease (GORD) and oesophagitis, relieves symptoms caused by excess gastric acid like heartburn and dyspepsia; as well as helping damaged tissues caused by excess acid to heal.

Panzop Relief for peptic ulcers

Panzop Relief tablets 40mg contain the active ingredient pantoprazole, which is used to treat and prevent peptic ulcers in the stomach (gastric ulcers or damage to the stomach lining) and duodenum (duodenal ulcers or damage to the lining of the upper intestine), caused by excess secretion of gastric acid; also gastric ulcers caused by use of nonsteroidal anti-inflammatory drugs (NSAID).  Panzop Relief tablets 40mg are also used as combination therapy to treat and prevent gastric ulcers that are caused by infection of the stomach with the bacterium Helicobacter pylori, in conjunction with using antibiotics.  Pantoprazole in Panzop Relief 40 reduces acid secretion by parietal cells of the stomach wall, by blocking the action of the enzyme H⁺/K⁺-ATPase, which is responsible for acid production.  This action of pantoprazole in Panzop Relief tablets 40mg reduces the acidity of the stomach contents, which reduces acid damage to the stomach wall and allows ulcers that have already developed to heal.  

What are the side effects of Panzop Relief?

The most commonly reported side effects when taking Panzop Relief tablets 40mg include constipation, nausea, vomiting, diarrhoea, wind (flatulence), headache, skin rash, dizziness, insomnia, dry mouth.

When should Panzop Relief not be used?

You should not use Panzop Relief tablets 40mg if you:

• are allergic to pantoprazole any other proton pump inhibitor or any ingredients in Panzop Relief
• are pregnant or are breastfeeding
• have kidney or liver disease, without discussion with your doctor
• are taking the anticoagulant warfarin, without discussion with your doctorare taking medicines that interact with Panzop Relief including the antifungals ketoconazole and itraconazole, the antiretroviral atazanavir

How should Panzop Relief be taken?

You should take your Panzop Relief tablets 40mg once daily swallowed whole with a glass of water and with food.  The dose you take and for how long depends on what you are being treated for and your doctor’s recommendation.  You should continue to take your Panzop Relief tablet 40mg for as long as recommended by your doctor, usually for a few weeks to 6 months, depending on your condition.

How long should you take Panzop Relief?

You should continue to take your Panzop Relief tablet 40mg for as long as recommended by your doctor, usually for a few weeks to 6 months, depending on your condition.

Missed dose of Panzop Relief

If you miss a dose of Panzop Relief tablets 40mg take it as soon as you remember, unless it is time to take the next dose, then skip the missed dose.  Do not take a double dose.

How should Panzop Relief be stored?

You should store your Panzop Relief tablets 40mg below 25°C in a cool dry place.