Deolate (Terbinafine 250mg) Tablets

Deolate general information

What is Deolate used for?

Deolate tablets 250mg are used to treat a variety of fungal skin infections, in several parts of the body, including onychomycosis, a fungal infection of the finger and/or toe nails, also called tinea unguium, and caused by the dermatophyte Trichophyton rubrum and the yeast fungus Candida albicans.  Deolate tablets 250mg are also used to treat fungal infections of the skin caused by the dermatophyte fungus Tinea, also known as ringworm, including, ringworm of the foot, also known as Athlete's foot (tinea pedis), of the body (tinea corporis), of the groin (tinea cruris or jock itch), of the scalp (tinea capitis).  Deolate tablets 250mg are also used to treat yeast infections of the skin caused by the yeast fungus Candida albicans, also known as candidiasis or thrush, where oral therapy is necessary due to the site, severity, or extent of the infection.  Deolate tablets 250mg relieve symptoms caused by the infection, including, itching, inflammation, redness, peeling and cracking or the skin.

How does Deolate work?

Deolate tablets 250mg contain terbinafine, a broad spectrum antifungal drug that is used to treat a variety of fungal infections and is particularly effective against dermatophyte fungi such as Trichophyton fungi that cause tinea infections in different parts of the body; also yeasts like Candida that cause candidiasis or thrush.  Terbinafine in Deolate tablets 250mg inhibits a fungal enzyme, squalene epoxidase, which prevents the synthesis of ergosterol, a sterol that is the main component of the fungal cell membrane.  The result is that the fungal cell membrane becomes weakened causing the cell contents to leak out, which kills the fungus and prevents the infection from spreading, relieving symptoms caused by the infection, including, itching and inflammation.  Terbinafine in Terbinafine tablets 250mg concentrates rapidly in skin, hair and nails reaching levels that kills the fungal infection. 

What does Deolate contain?

Deolate tablets 250mg contains the active ingredient t terbinafine, a broad spectrum antifungal drug that is used to treat a variety of fungal infections.  They also contain, colloidal silicon dioxide, hypromellose, magnesium stearate, microcrystalline cellulose, sodium starch glycolate.

Treating fungal infections with Deolate

Deolate tablets 250mg contain terbinafine, a broad spectrum antifungal drug that is used to treat a variety of fungal infections and is particularly effective against fungi that cause tinea infections or ringworm.  Several parts of the body can be affected, and the fungus is often named after the site of infection; these include, ringworm of the foot, also known as Athlete's foot (tinea pedis), of the body (tinea corporis), of the groin (tinea cruris or jock itch), of the scalp (tinea capitis); also fungal infections of the finger nails and toe nails (onychomycosis).  Terbinafine in Deolate tablets 250mg inhibits a fungal enzyme, squalene epoxidase, which prevents the synthesis of ergosterol, the main component of the fungal cell membrane.  Terbinafine tablets 250mg kills the fungus and prevents the infection from spreading, relieving symptoms caused by the infection, including, itching and inflammation.  

What are the side effects of Deolate?

The most commonly reported side effects when taking Deolate tablets 250mg include nausea, vomiting, upset stomach, loss of appetite, diarrhoea headache, aching joints or muscles, dizziness or light-headedness, tiredness, sleepiness, taste changes.

When should Deolate not be used?

You should not use Deolate tablets 250mg if you:

• are allergic to terbinafine or any ingredients in Deolate
• are pregnant or are breastfeeding
• have kidney or liver disease
• are taking medicines that interact with Deolate, including cimetidine for stomach ulcers, the antibiotic rifampicin, oral contraceptives, antidepressants including tricyclic antidepressants like desipramine and selective serotonin reuptake inhibitors (SSRI), beta-blockers for heart problems and high blood pressure, antiarrhythmics like flecainide, the immunosuppressant cyclosporine, caffeine for headaches

What medications interact with Deolate?

Several medications interact with Deolate tablets 250mg and should either not be taken while you are taking Deolate or only after discussion and instruction from your doctor:

• Drugs that affect Deolate: cimetidine for stomach ulcers, the antibiotic rifampicin
• Drugs that are affected by Deolate: oral contraceptives, antidepressants including tricyclic antidepressants like desipramine and selective serotonin reuptake inhibitors (SSRI), beta-blockers for heart problems and high blood pressure, antiarrhythmics like flecainide, the immunosuppressant cyclosporine, caffeine for headaches

How should Deolate be taken?

You should take your Deolate tablets 250mg swallowed whole with a glass of water and with food, once daily at the same time each day.  The duration of your treatment depends on what you are being treated for, the severity of your condition and your doctor’s recommendations.  For most fungal infections you should continue to take your Deolate tablets 250mg for 2-6 weeks until the infection has cleared up; for nail infections it may take up to 3 months.

How long should you take Deolate?

For most fungal infections you should continue to take your Deolate tablets 250mg for 2-6 weeks until the infection has cleared up; for nail infections it may take up to 3 months.

Missed dose of Deolate

If you miss a dose of Deolate tablets 250mg take it as soon as you remember, unless it is time to take the next dose, then skip the missed dose.  Do not take a double dose.

How should Deolate be stored?

You should store your Deolate tablets 250mg below 25°C in a cool dry place.